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PDCD4-bound mRNA profile in T lymphocytes
(Universitätskinderklinik (HL, MB-W) und Institut für Genetik (DS, MZ), Medizinische Fakultät, OVGU Magdeburg, 2017)
The blockade of inhibitory receptors such as CTLA-4 (CD152) is being used as immune-checkpoint therapy, offering a powerful strategy to restore effective immune responses against tumors. To determine signal components ...